TUBB

Gene

tubulin beta class I

HGNCHGNC:20778 EnsemblENSG00000196230 NCBI Gene203068

Locus: gene with protein productLocation: 6p21.33

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Tubulin beta chainP07437

Protein · therapeutic target

Clinically validated target · 25 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMGC16435 · M40 · Tubb5 · OK/SW-cl.56

View full nomenclature history (9)

Alias symbolsMGC16435, M40, Tubb5, OK/SW-cl.56

Previous namestubulin, beta polypeptide, tubulin, beta, tubulin, beta class I

Alias namesclass I beta-tubulin, beta1-tubulin

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Multiple benign circumferential skin creases on limbs 1

Complex cortical dysplasia with other brain malformations 6

Genetic central nervous system malformation

Breast Neoplasms

Carcinoma, Non-Small-Cell Lung

Neoplasms

Prostatic Neoplasms

Hodgkin's Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Tubulin beta family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.