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TUBB2A

Gene

tubulin beta 2A class IIa

HGNCHGNC:12412EnsemblENSG00000137267NCBI Gene7280
Locus: gene with protein productLocation: 6p25.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Tubulin beta-2A chainQ13885

Protein · therapeutic target

Clinically validated target · 25 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTUBB2 · TUBB · dJ40E16.7
View full nomenclature history (7)
Previous symbolsTUBB2, TUBB
Alias symbolsdJ40E16.7
Previous namestubulin, beta polypeptide, tubulin, beta 2, tubulin, beta 2A
Alias namesclass IIa beta-tubulin

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Complex cortical dysplasia with other brain malformations 5
Genetic central nervous system malformation
Breast Neoplasms
Carcinoma, Non-Small-Cell Lung
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Tubulin beta family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.