TUBB8

Gene

tubulin beta 8 class VIII

HGNCHGNC:20773 EnsemblENSG00000261456 NCBI Gene347688

Locus: gene with protein productLocation: 10p15.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Tubulin beta-8 chainQ3ZCM7

Protein · therapeutic target

Clinically validated target · 25 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asbA631M21.2

View full nomenclature history (3)

Alias symbolsbA631M21.2

Previous namestubulin, beta 8 class VIII

Alias namesclass VIII beta-tubulin

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Female infertility due to fertilization defect

Carcinoma, Non-Small-Cell Lung

Breast Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Tubulin beta family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.