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TWIST2

Gene

twist family bHLH transcription factor 2

HGNCHGNC:20670EnsemblENSG00000233608NCBI Gene117581
Locus: gene with protein productLocation: 2q37.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDERMO1 · Dermo-1 · bHLHa39
View full nomenclature history (5)
Alias symbolsDERMO1, Dermo-1, bHLHa39
Previous namestwist homolog 2 (Drosophila), twist basic helix-loop-helix transcription factor 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Alopecia
Genetic Diseases, Inborn
Hair color
Pulmonary Disease, Chronic Obstructive

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Basic helix-loop-helix proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.