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UBE2E3

Gene

ubiquitin conjugating enzyme E2 E3

HGNCHGNC:12479EnsemblENSG00000170035NCBI Gene10477
Locus: gene with protein productLocation: 2q31.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asUbcH9
View full nomenclature history (4)
Alias symbolsUbcH9
Previous namesubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5), ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast), ubiquitin-conjugating enzyme E2E 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hypertension
Diabetes Mellitus, Type 2
Neurodegenerative Diseases
Smoking cessation
Muscular dystrophy
Atrial Fibrillation
Diabetic Neuropathies
Psoriasis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ubiquitin conjugating enzymes E2

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.