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VPS45

Gene

vacuolar protein sorting 45 homolog

HGNCHGNC:14579EnsemblENSG00000136631NCBI Gene11311
Locus: gene with protein productLocation: 1q21.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asVPS45B · VPS45A · h-vps45 · H1
View full nomenclature history (7)
Previous symbolsVPS45B, VPS45A
Alias symbolsh-vps45, H1
Previous namesvacuolar protein sorting 45A (yeast homolog), vacuolar protein sorting 45A (yeast), vacuolar protein sorting 45 homolog (S. cerevisiae)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Severe congenital neutropenia
Neurodegenerative Diseases
COVID-19
Genetic Diseases, Inborn
Schizophrenia
Venous Thrombosis
Carcinoma, Hepatocellular

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.