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WARS2

Gene

tryptophanyl tRNA synthetase 2, mitochondrial

HGNCHGNC:12730EnsemblENSG00000116874NCBI Gene10352
Locus: gene with protein productLocation: 1p12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asmtTrpRS
View full nomenclature history (2)
Alias symbolsmtTrpRS
Alias namestryptophan tRNA ligase 2, mitochondrial

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Genetic Diseases, Inborn
Alopecia
Mitochondrial Diseases
Infantile dystonia-parkinsonism
Parkinsonism-dystonia, infantile
Colorectal Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Aminoacyl tRNA synthetases, Class I

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.