WNK1

Gene

WNK lysine deficient protein kinase 1

HGNCHGNC:14540 EnsemblENSG00000060237 NCBI Gene65125

Locus: gene with protein productLocation: 12p13.33

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPRKWNK1 · HSN2 · HSAN2 · PPP1R167

View full nomenclature history (7)

Previous symbolsPRKWNK1, HSN2

Alias symbolsHSAN2, PPP1R167

Previous namesprotein kinase, lysine deficient 1, hereditary sensory neuropathy, type II

Alias namesprotein phosphatase 1, regulatory subunit 167

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hereditary sensory and autonomic neuropathy type 2

Neurodegenerative Diseases

Genetic Diseases, Inborn

Hereditary sensory and autonomic neuropathy

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Protein phosphatase 1 regulatory subunitsMinor histocompatibility antigensWNK lysine deficient protein kinases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.

Open TargetsGene–disease associations from the Open Targets Platform.