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WRAP53

Gene

WD repeat containing antisense to TP53

HGNCHGNC:25522EnsemblENSG00000141499NCBI Gene55135
Locus: gene with protein productLocation: 17p13.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asWDR79 · FLJ10385 · TCAB1
View full nomenclature history (7)
Previous symbolsWDR79
Alias symbolsFLJ10385, TCAB1
Previous namesWD repeat domain 79, WD repeat containing, antisense to TP53
Alias namestelomerase cajal body protein 1, WD-encoding RNA antisense to p53

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Dyskeratosis congenita
Neurodegenerative Diseases
Inherited cancer-predisposing syndrome
Neoplastic Syndromes, Hereditary
Alzheimer's Disease
Lysosomal Storage Diseases
Multiple Sclerosis
Parkinson's Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

WD repeat domain containingTelomerase holoenzyme subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.