XPR1

Gene

xenotropic and polytropic retrovirus receptor 1

HGNCHGNC:12827 EnsemblENSG00000143324 NCBI Gene9213

Locus: gene with protein productLocation: 1q25.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSYG1 · X3 · SLC53A1

View full nomenclature history (5)

Alias symbolsSYG1, X3, SLC53A1

Previous namesxenotropic and polytropic retrovirus receptor

Alias namessolute carrier family 53 (phosphate exporter), member 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Bilateral striopallidodentate calcinosis

Central Nervous System Neoplasms

Ovarian carcinoma

Genetic Diseases, Inborn

Spondylitis, Ankylosing

Ovarian dysfunction

Ovarian Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Solute carrier family 53

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-14.

Open TargetsGene–disease associations from the Open Targets Platform.