Protein / target

DNA repair protein RAD51 homolog 1

RAD51Q06609
UniProt: Q06609
32
Research papers

Protein at a glance

Research activity

Actively researched

32 papers · latest 2026

Derived from structured UniProt, Open Targets and literature data on this page.

Research activity

32 papers · to 2026

Papers linked directly to this protein. This is the protein's own literature — descriptor-derived papers are kept separate below.

Most cited

Genetic mechanisms of critical illness in COVID-19.1,129 cites

Pairo-Castineira E · Nature · 2021

The cGAS-STING pathway drives type I IFN immunopathology in COVID-19.465 cites

Domizio JD · Nature · 2022

NAD<sup>+</sup> supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer's disease via cGAS-STING.387 cites

Hou Y · Proceedings of the National Academy of Sciences of the United States of America · 2021

Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models.282 cites

Kim H · Nature communications · 2020

Activating cGAS-STING pathway for the optimal effect of cancer immunotherapy.277 cites

Li A · Journal of hematology & oncology · 2019

Recent

Programmable genome editing in human cells using RNA-guided bridge recombinases.

Pelea O · Science (New York, N.Y.) · 2026

Integration of therapeutic cargo into the human genome with programmable type V-K CAST.

Liu J · Nature communications · 2025

Systematic optimization and prediction of cre recombinase for precise genome editing in mice.

Erhardt V · Genome biology · 2025

Bridging innate and adaptive tumor immunity: cGAS-STING pathway activation to potentiate immune checkpoint blockade.

Li Z · Journal of experimental & clinical cancer research : CR · 2025

A disease-specific convergence of host and Epstein-Barr virus genetics in multiple sclerosis.

Mechelli R · Proceedings of the National Academy of Sciences of the United States of America · 2025

Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing.

Pandey S · Nature biomedical engineering · 2025

Demystifying the cGAS-STING pathway: precision regulation in the tumor immune microenvironment.

Wang Q · Molecular cancer · 2025

Serine Depletion Promotes Antitumor Immunity by Activating Mitochondrial DNA-Mediated cGAS-STING Signaling.

Saha S · Cancer research · 2024

Flexible TAM requirement of TnpB enables efficient single-nucleotide editing with expanded targeting scope.

Feng X · Nature communications · 2024

Transposase-assisted target-site integration for efficient plant genome engineering.

Liu P · Nature · 2024

Europe PMC papers linked directly to this protein.