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RAD51

Gene

RAD51 recombinase

HGNCHGNC:9817EnsemblENSG00000051180NCBI Gene5888
Locus: gene with protein productLocation: 15q15.1

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

DNA repair protein RAD51 homolog 1Q06609

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRAD51A · RECA · HsRad51 · HsT16930 · BRCC5 · FANCR
View full nomenclature history (10)
Previous symbolsRAD51A, RECA
Alias symbolsHsRad51, HsT16930, BRCC5, FANCR
Previous namesRAD51 (S. cerevisiae) homolog (E coli RecA homolog), RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae), RAD51 homolog (S. cerevisiae)
Alias namesBRCA1/BRCA2-containing complex, subunit 5

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Fanconi Anemia
Neoplasms
Genetic Diseases, Inborn
Alcohol drinking

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

FA complementation groupsRAD51 paralogs

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.