Protein / target

Tyrosine-protein phosphatase non-receptor type 11

PTPN11Q06124
UniProt: Q06124
11
Research papers

Protein at a glance

Research activity

Emerging research

11 papers · latest 2025

Derived from structured UniProt, Open Targets and literature data on this page.

Research activity

11 papers · to 2025

Papers linked directly to this protein. This is the protein's own literature — descriptor-derived papers are kept separate below.

Most cited

Phenotypic and functional separation of memory and effector human CD8+ T cells.1,003 cites

Hamann D · The Journal of experimental medicine · 1997

The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state.973 cites

Kurutas EB · Nutrition journal · 2016

PROVENGE (Sipuleucel-T) in prostate cancer: the first FDA-approved therapeutic cancer vaccine.548 cites

Cheever MA · Clinical cancer research : an official journal of the American Association for Cancer Research · 2011

The MAPK/ERK cascade targets both Elk-1 and cAMP response element-binding protein to control long-term potentiation-dependent gene expression in the dentate gyrus in vivo.494 cites

Davis S · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000

Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8<sup>+</sup> T cell exhaustion.335 cites

Peng DH · Nature communications · 2020

Recent

Synaptic and Non-Synaptic Functions of PTPRD: A Receptor Tyrosine Phosphatase at the Crossroads of Neural Circuitry and Metabolism.

Kim S · Journal of neurochemistry · 2025

The genetics of Graves' disease.

Grixti L · Reviews in endocrine & metabolic disorders · 2024

PTPRS is a novel marker for early Tau pathology and synaptic integrity in Alzheimer's disease.

Poirier A · Scientific reports · 2024

SHP2: A Pleiotropic Target at the Interface of Cancer and Its Microenvironment.

Sodir NM · Cancer discovery · 2023

The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity.

Baumgartner CK · Nature · 2023

ERK: A Double-Edged Sword in Cancer. ERK-Dependent Apoptosis as a Potential Therapeutic Strategy for Cancer.

Sugiura R · Cells · 2021

Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8<sup>+</sup> T cell exhaustion.

Peng DH · Nature communications · 2020

The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state.

Kurutas EB · Nutrition journal · 2016

PROVENGE (Sipuleucel-T) in prostate cancer: the first FDA-approved therapeutic cancer vaccine.

Cheever MA · Clinical cancer research : an official journal of the American Association for Cancer Research · 2011

The MAPK/ERK cascade targets both Elk-1 and cAMP response element-binding protein to control long-term potentiation-dependent gene expression in the dentate gyrus in vivo.

Davis S · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000

Europe PMC papers linked directly to this protein.