Angioedemas, Hereditary
Recent clinical, regulatory, research and industry developments relating to this disease.
CRISPR-Cas9 In Vivo Gene Editing of <i>KLKB1</i> for Hereditary Angioedema.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes3
- Angioedemas, Hereditary1
- CRISPR-Cas Systems1
- Gene Editing1
Leading journals1
- The New England journal of medicine1
Leading researchers8
- Abdelhady AM1
- Boiselle C1
- Butler JS1
- Clark ED1
- Cohn DM1
- Fijen LM1
- Golden A1
- Gurugama P1
Affiliations (unnormalised)1
- Auckland City Hospital (H.J.L.1
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Disease biology
Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.
Reference
Authoritative identity, definition & identifiers.
Inherited disorders that are characterized by subcutaneous and submucosal EDEMA in the upper RESPIRATORY TRACT and GASTROINTESTINAL TRACT.
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.