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Disease

autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency

Also known as ALPS due to CTLA4 haploinsufficiency, ALPS type 5, ALPS type V, CHAI+10 more

ALPS due to CTLA4 haploinsufficiency, ALPS type 5, ALPS type V, CHAI, CTLA-4 haploinsufficiency with autoimmune infiltration disease, CTLA4 haploinsufficiency, autoimmune lymphoproliferative syndrome type 5, autoimmune lymphoproliferative syndrome type V, chai, immune dysregulation with autoimmunity, immunodeficiency, and lymphoproliferation, ALPS5, CTLA4 haploinsufficiency with autoimmune infiltration, autoimmune lymphoproliferative syndrome, type 5, autoimmune lymphoproliferative syndrome, type V.

6
Associated genes
1
Related proteins

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 2 industry developments reported.
Major developments
Partnership announcedWorth watching
Partnership · STAT News2026-06-24
Activity timeline2

Associated genes

6 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

Disease biology

1 match

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Reference

Authoritative identity, definition & identifiers.

Synonyms

ALPS due to CTLA4 haploinsufficiency, ALPS type 5, ALPS type V, CHAI, CTLA-4 haploinsufficiency with autoimmune infiltration disease, CTLA4 haploinsufficiency, autoimmune lymphoproliferative syndrome type 5, autoimmune lymphoproliferative syndrome type V, chai, immune dysregulation with autoimmunity, immunodeficiency, and lymphoproliferation, ALPS5, CTLA4 haploinsufficiency with autoimmune infiltration, autoimmune lymphoproliferative syndrome, type 5, autoimmune lymphoproliferative syndrome, type V

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.