GKN2

Gene

gastrokine 2

HGNCHGNC:24588 EnsemblENSG00000183607 NCBI Gene200504

Locus: gene with protein productLocation: 2p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTFIZ1 · PRO813 · VLTI465 · blottin · GDDR · BRICD1B

View full nomenclature history (8)

Alias symbolsTFIZ1, PRO813, VLTI465, blottin, GDDR, BRICD1B

Alias namesdown regulated in gastric cancer GDDR, BRICHOS domain containing 1B

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Stomach Neoplasms

Neoplasms

Carcinoma, Non-Small-Cell Lung

Gastric adenocarcinoma

Gastric carcinoma

Barrett Esophagus

Lung carcinoma

autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

BRICHOS domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.