GFUS

Gene

GDP-L-fucose synthase

HGNCHGNC:12390 EnsemblENSG00000104522 NCBI Gene7264

Locus: gene with protein productLocation: 8q24.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTSTA3 · FX · P35B · SDR4E1

View full nomenclature history (6)

Previous symbolsTSTA3

Alias symbolsFX, P35B, SDR4E1

Previous namestissue specific transplantation antigen P35B

Alias namesshort chain dehydrogenase/reductase family 4E, member 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Esophageal Squamous Cell Carcinoma

autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Short chain dehydrogenase/reductase superfamily

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.