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Disease

Chronic Kidney Disease-Mineral and Bone Disorder

Late-stage therapeutic developmentEmerging research
1
Publications
1
Clinical trials
12
Associated genes
1
Related proteins
2008
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

Chronic kidney disease mineral and bone disorder in children.

Research2007-11-28Pediatric nephrology (Berlin, Germany)

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial with recent milestones.
Major developments
Major clinical milestoneHigh impact
Primary completion2026-09-01
Clinical Milestones1View

Clinical trials

1 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
1
All trials
1
Active
1
Late-stage
0
Completed

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

Chronic kidney disease mineral and bone disorder in children.

Pediatric nephrology (Berlin, Germany) · 2008 · 47 cites
Recent publications

Chronic kidney disease mineral and bone disorder in children.

Pediatric nephrology (Berlin, Germany) · 2008 · 47 cites
Leading journals1
  • Pediatric nephrology (Berlin, Germany)1
Leading researchers3
  • Bakkaloglu S1
  • Salusky I1
  • Wesseling K1
Affiliations (unnormalised)1
  • David Geffen School of Medicine at UCLA1

Associated genes

12 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

Disease biology

1 match

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Decalcification of bone or abnormal bone development due to chronic KIDNEY DISEASES, in which 1,25-DIHYDROXYVITAMIN D3 synthesis by the kidneys is impaired, leading to reduced negative feedback on PARATHYROID HORMONE. The resulting SECONDARY HYPERPARATHYROIDISM eventually leads to bone disorders.

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.