FRAT2

Gene

FRAT regulator of Wnt signaling pathway 2

HGNCHGNC:16048 EnsemblENSG00000181274 NCBI Gene23401

Locus: gene with protein productLocation: 10q24.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

View full nomenclature history (4)

Previous namesFRAT regulator of WNT signaling pathway 2, frequently rearranged in advanced T-cell lymphomas 2, FRAT2, WNT signaling pathway regulator

Alias namesGSK-3 binding protein FRAT2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Chronic Kidney Disease-Mineral and Bone Disorder

Diabetes Mellitus, Type 2

Risk-taking behaviour

Intelligence

Diabetes Mellitus

Non-alcoholic Fatty Liver Disease

Neoplasms

Uterine Cervical Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-06-27.

Open TargetsGene–disease associations from the Open Targets Platform.