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Disease

Dyspepsia

Late-stage therapeutic developmentEmerging research
MeSHDyspepsia
1
Publications
22
Clinical trials
2017
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Moderate
Key developments
  • 5 clinical trials expected to report results, the earliest in Q4 2026.
Upcoming Milestones
Clinical Milestones8View
Results posted 1
Results expected 5
Recently completed 2
Activity timeline8

Clinical trials

17 sponsors · 4 new · 1 completed in the last 12 months (net +4)

The current development programme across all trial phases.

Clinical programme
22
All trials
6
Active
17
Late-stage
6
Completed
Late-stage studies

Comparing Intravenous Famotidine and Oral Antacids in the Treatment of Dyspepsia in the Emergency Department

Phase 4 · Recruiting · Stony Brook University

Efficacy of Clostridium Butyricum in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia：A Prospective, Double-Blind, Randomized, Placebo-Controlled Clinical Trial

Phase 4 · Recruiting · Xijing Hospital of Digestive Diseases

Efficacy of Bacillus Coagulans in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia：A Prospective, Double-Blind, Randomized, Placebo-Controlled Clinical Trial

Phase 4 · Recruiting · Xijing Hospital of Digestive Diseases

Evaluation of The Effect of Holy Basil in The Treatment of Patients With Dyspepsia

Phase 2/3 · Recruiting · Mahidol University

Multi-center, Randomized, Double-blind, Placebo Controlled, Parallel Clinical Trial for the Evauation of the Efficacy and Safety of CnU Cap. 500 mg in Patients With Biliary Dyspepsia

Phase 4 · Recruiting · Myungmoon Pharma. Co. Ltd.

Double-blind, Placebo-controlled, Cross-over Trial of Ketotifen in Children and Adolescents With Functional Dyspepsia in Association With Duodenal Eosinophilia

Phase 3 · Recruiting · Craig A. Friesen, MD
Recruiting

Comparing Intravenous Famotidine and Oral Antacids in the Treatment of Dyspepsia in the Emergency Department

Phase 4 · Recruiting · Stony Brook University

Efficacy of Clostridium Butyricum in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia：A Prospective, Double-Blind, Randomized, Placebo-Controlled Clinical Trial

Phase 4 · Recruiting · Xijing Hospital of Digestive Diseases

Efficacy of Bacillus Coagulans in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia：A Prospective, Double-Blind, Randomized, Placebo-Controlled Clinical Trial

Phase 4 · Recruiting · Xijing Hospital of Digestive Diseases

Evaluation of The Effect of Holy Basil in The Treatment of Patients With Dyspepsia

Phase 2/3 · Recruiting · Mahidol University

Multi-center, Randomized, Double-blind, Placebo Controlled, Parallel Clinical Trial for the Evauation of the Efficacy and Safety of CnU Cap. 500 mg in Patients With Biliary Dyspepsia

Phase 4 · Recruiting · Myungmoon Pharma. Co. Ltd.

Double-blind, Placebo-controlled, Cross-over Trial of Ketotifen in Children and Adolescents With Functional Dyspepsia in Association With Duodenal Eosinophilia

Phase 3 · Recruiting · Craig A. Friesen, MD
Recently completed

Randomized Controlled Trial of DLBS2411 Treatment For Functional Dyspepsia

Phase 3 · Completed · Dexa Medica Group

Perceived Changes in Symptom Burden and Physiological Effects of a Proprietary Phyto-therapeutic Preparation (Amara) in Patients With Functional Dyspepsia: Prospective Study as Investigator Initiated Trial (IIT)

Phase 4 · Completed · Mark Fox

Randomized Multicentre Open-label Study to Investigate the Non-inferiority of Itopride Hydrochloride 150mg Once Daily Versus Itopride Hydrochloride 50 mg Thrice Daily in Subjects With Functional (Non-ulcer) Dyspepsia or Chronic Gastritis

Phase 3 · Completed · Abbott

Evaluation on the Influence of Shenqu Xiaoshi Oral Liquid for the Intestinal Microbiome of Children With Functional Dyspepsia

Phase 4 · Completed · Ruijin Hospital

Rescue Therapy for Helicobacter Pylori Eradication: A Randomized and Non-inferiority Trail of Vonorazon and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy

Phase 4 · Completed · Yongquan Shi

Duodenal Neuro-immune Interactions and Effects of PPI in Functional Dyspepsia

Phase 4 · Completed · Universitaire Ziekenhuizen KU Leuven

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Major themes1
  • Helicobacter pylori1
Leading journals1
  • Gut1
Leading researchers8
  • Atherton J1
  • Axon AT1
  • Bazzoli F1
  • El-Omar EM1
  • Gasbarrini A1
  • Gisbert JP1
  • Graham DY1
  • Hunt R1
Affiliations (unnormalised)6
  • Erasmus University Medical Center1
  • General Infirmary Leeds1
  • Henry Dunant Hospital1
  • Hospital Universitario de La Princesa1
  • Institut für Medizinische Mikrobiologie1
  • Jichi Medical School1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Impaired digestion, especially after eating.

Identifiers
MeSHDyspepsia
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.