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Disease
Dyspepsia
Late-stage therapeutic developmentEmerging research
1
Publications
22
Clinical trials
12
Associated genes
3
Related proteins
2017
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Moderate
Key developments
- 6 clinical trials expected to report results, the earliest in Q4 2026.
Upcoming Milestones
- Q4 2026Efficacy of Bacillus Coagulans in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia：A Prospective, Double-Blind, Randomized, Placebo-Controlled Clinical Trial
- Q4 2026Efficacy of Clostridium Butyricum in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia：A Prospective, Double-Blind, Randomized, Placebo-Controlled Clinical Trial
- Q4 2026Evaluation of The Effect of Holy Basil in The Treatment of Patients With Dyspepsia
- Q2 2027Double-blind, Placebo-controlled, Cross-over Trial of Ketotifen in Children and Adolescents With Functional Dyspepsia in Association With Duodenal Eosinophilia
- Q4 2027Comparing Intravenous Famotidine and Oral Antacids in the Treatment of Dyspepsia in the Emergency Department
Major developments
Upcoming trial readoutHigh impact
Results expected Q4 20272026-07-29
Upcoming trial readoutHigh impact
Results expected Q4 20272026-06-02
Clinical MilestonesView all 9Hide
Results posted
Results expected
- 2026-07-29Multi-center, Randomized, Double-blind, Placebo Controlled, Parallel Clinical Trial for the Evauation of the Efficacy and Safety of CnU Cap. 500 mg in Patients With Biliary DyspepsiaResults expected Q4 2027
- 2026-06-02Comparing Intravenous Famotidine and Oral Antacids in the Treatment of Dyspepsia in the Emergency DepartmentResults expected Q4 2027
- 2026-03-24Evaluation of The Effect of Holy Basil in The Treatment of Patients With DyspepsiaResults expected Q4 2026
- 2026-01-09Double-blind, Placebo-controlled, Cross-over Trial of Ketotifen in Children and Adolescents With Functional Dyspepsia in Association With Duodenal EosinophiliaResults expected Q2 2027
- 2026-01-05Efficacy of Bacillus Coagulans in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia：A Prospective, Double-Blind, Randomized, Placebo-Controlled Clinical TrialResults expected Q4 2026
Recently completed
+1 more in the activity timeline below
Activity timeline9
- 2026-07-29ClinicalMulti-center, Randomized, Double-blind, Placebo Controlled, Parallel Clinical Trial for the Evauation of the Efficacy and Safety of CnU Cap. 500 mg in Patients With Biliary DyspepsiaResults expected Q4 2027
- 2026-06-02ClinicalComparing Intravenous Famotidine and Oral Antacids in the Treatment of Dyspepsia in the Emergency DepartmentResults expected Q4 2027
- 2026-05-08ClinicalZ-338 Phase III Trial - Evaluation of Pharmacokinetics, Efficacy and Safety in Paediatric Patients With Functional DyspepsiaCompleted
- 2026-04-03ClinicalRandomized Multicentre Open-label Study to Investigate the Non-inferiority of Itopride Hydrochloride 150mg Once Daily Versus Itopride Hydrochloride 50 mg Thrice Daily in Subjects With Functional (Non-ulcer) Dyspepsia or Chronic GastritisResults posted
- 2026-03-24ClinicalEvaluation of The Effect of Holy Basil in The Treatment of Patients With DyspepsiaResults expected Q4 2026
- 2026-01-09ClinicalDouble-blind, Placebo-controlled, Cross-over Trial of Ketotifen in Children and Adolescents With Functional Dyspepsia in Association With Duodenal EosinophiliaResults expected Q2 2027
- 2026-01-05ClinicalEfficacy of Bacillus Coagulans in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia：A Prospective, Double-Blind, Randomized, Placebo-Controlled Clinical TrialResults expected Q4 2026
- 2026-01-05ClinicalEfficacy of Clostridium Butyricum in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia：A Prospective, Double-Blind, Randomized, Placebo-Controlled Clinical TrialResults expected Q4 2026
- 2025-10-01ClinicalRandomized Controlled Trial of DLBS2411 Treatment For Functional DyspepsiaCompleted
Clinical trials
The current development programme across all trial phases.
Clinical programme
22
6
17
6
Late-stage studies
Recruiting
Recently completed
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Most influential
Major themes1
- Helicobacter pylori1
Leading journals1
- Gut1
Leading researchers8
- Atherton J1
- Axon AT1
- Bazzoli F1
- El-Omar EM1
- Gasbarrini A1
- Gisbert JP1
- Graham DY1
- Hunt R1
Affiliations (unnormalised)6
- Erasmus University Medical Center1
- General Infirmary Leeds1
- Henry Dunant Hospital1
- Hospital Universitario de La Princesa1
- Institut für Medizinische Mikrobiologie1
- Jichi Medical School1
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Disease biology
Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
Impaired digestion, especially after eating.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.