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PTPRZ1

Gene

protein tyrosine phosphatase receptor type Z1

HGNCHGNC:9685EnsemblENSG00000106278NCBI Gene5803
Locus: gene with protein productLocation: 7q31.32

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPTPZ · PTPRZ · PTP18 · RPTPB · phosphacan
View full nomenclature history (6)
Previous symbolsPTPZ, PTPRZ
Alias symbolsPTP18, RPTPB, phosphacan
Previous namesprotein tyrosine phosphatase, receptor-type, Z polypeptide 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Placental retention
Dyspepsia
Diabetes Mellitus
Metabolic Diseases
Ovarian neoplasm

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Fibronectin type III domain containingProtein tyrosine phosphatases receptor type

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.