Pregnancy Complications, Infectious
Recent clinical, regulatory, research and industry developments relating to this disease.
The impact of the COVID-19 pandemic on maternal and perinatal health: a scoping review.
Analysis of SARS-CoV-2 vertical transmission during pregnancy.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 1 clinical trial expected to report results, the earliest in Q2 2029.
Clinical MilestonesViewHide
- 2025-12-18Azithromycin and Ampicillin for Late PPROMResults expected Q2 2029
- 2025-12-18ClinicalAzithromycin and Ampicillin for Late PPROMResults expected Q2 2029
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes8
- Pregnancy Complications, Infectious2
- Betacoronavirus1
- Coronavirus Infections1
- COVID-191
- Infectious Disease Transmission, Vertical1
- Maternal Health1
- Maternal Health Services1
- Pandemics1
Leading journals5
- European heart journal1
- Nature communications1
- Physiological reviews1
- Reproductive health1
- Viruses1
Leading researchers8
- Beretta I1
- Biasin M1
- Blomstrom Lundqvist C1
- Borghi C1
- Callegari C1
- Cammarata S1
- Cetin I1
- Cifkova R1
Affiliations (unnormalised)6
- Brown University1
- Clinical Microbiology1
- Department of Biological and Clinical Sciences1
- Department of Biomedical and Clinical Sciences1
- George Washington University1
- Harvard T.H. Chan School of Public Health1
Related conditions
Diseases frequently studied alongside this one. Number shows shared papers.
Disease profile
A grounded synthesis of the condition — overview, causes, mechanism, risk factors and current standard of care.
Pregnancy complications, infectious refers to the co-occurrence of pregnancy and an infection, whether the infection begins before fertilization or develops afterward. The literature frames this as a broad maternal-health condition with implications for pregnancy outcome, including effects on implantation, fetal growth and development, labor, and neonatal health.
The condition is caused by infection occurring in temporal association with pregnancy. The supplied grounding does not support a more specific aetiology beyond infectious co-occurrence, so no particular pathogens or transmission routes can be stated.
The biological impact is mediated through the interaction between infection and the physiologic changes of pregnancy. The literature notes that pregnancy alters immune, respiratory, cardiovascular, and coagulation systems, which may in turn influence infection severity and downstream pregnancy outcomes.
Pregnancy itself is the defining context for risk, because infection may occur before or after fertilization and complicate the course of gestation. The supplied grounding also indicates that asymptomatic infection can complicate service provision and prevention, but it does not support additional specific risk factors.
Management is described at the level of prevention, control, and therapy rather than specific regimens. The literature emphasizes surveillance and preventive measures, with treatment directed at the underlying infection and attention to maternal and perinatal outcomes.
AI-generated summary grounded in MeSH and 2 peer-reviewed sources. Informational only — not medical advice. Generated 2026-07-07.
Reference
Authoritative identity, definition & identifiers.
The co-occurrence of pregnancy and an INFECTION. The infection may precede or follow FERTILIZATION.
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.