Takayasu arteritis
Also known as Arteritis, Takayasu, Takayasu's arteritis, Takayasu's disease, aortic arch arteritis+8 more
Arteritis, Takayasu, Takayasu's arteritis, Takayasu's disease, aortic arch arteritis, aortic arch syndrome, cervical aortic arch, idiopathic aortitis, pharyngeal arch artery syndromic disease, TA, Takayasu disease, Young female arteritis, pulseless disease.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 4 clinical trials expected to report results, the earliest in Q3 2027.
- Q3 2027Dapagliflozin and Endothelin Receptor Antagonism in Large Vessel Vasculitis (DERAIL-LVV)
- Q4 2027Cessation of Biologic Treatment in Patients With Takayasu Arteritis in Sustained Remission
- Q4 2027Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine (Butantan-DV) in Patients With Autoimmune Rheumatic Diseases Living in Dengue-Endemic Areas
- Q3 2028A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Upadacitinib in Subjects With Takayasu Arteritis (SELECT-Takayasu)
Clinical MilestonesViewHide
- 2026-04-15Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine (Butantan-DV) in Patients With Autoimmune Rheumatic Diseases Living in Dengue-Endemic AreasResults expected Q4 2027
- 2026-03-25Cessation of Biologic Treatment in Patients With Takayasu Arteritis in Sustained RemissionResults expected Q4 2027
- 2026-02-18A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Upadacitinib in Subjects With Takayasu Arteritis (SELECT-Takayasu)Results expected Q3 2028
- 2026-01-14Dapagliflozin and Endothelin Receptor Antagonism in Large Vessel Vasculitis (DERAIL-LVV)Results expected Q3 2027
- 2026-06-30A Randomized, Controlled, Open-label, Multicenter Clinical Trial Comparing the Efficacy and Safety of a Precision Treatment Regimen Based on Clinical-molecular Phenotypes with a Conventional Treatment Regimen in the Treatment of Patients with Active Takayasu's ArteritisPrimary completion
- 2025-12-31Comparison of the Efficacy and Safety of Tofacitinib and Methotrexate Based on Prednisone Therapy in Patients with Active Phase of Takayasu's Arteritis: a Randomized Controlled TrialPrimary completion
- 2025-12-31Low Dose Naltrexone to Improve Physical Health in Patients With VasculitisCompleted
- 2026-06-30ClinicalA Randomized, Controlled, Open-label, Multicenter Clinical Trial Comparing the Efficacy and Safety of a Precision Treatment Regimen Based on Clinical-molecular Phenotypes with a Conventional Treatment Regimen in the Treatment of Patients with Active Takayasu's ArteritisPrimary completion
- 2026-04-15ClinicalSafety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine (Butantan-DV) in Patients With Autoimmune Rheumatic Diseases Living in Dengue-Endemic AreasResults expected Q4 2027
- 2026-03-25ClinicalCessation of Biologic Treatment in Patients With Takayasu Arteritis in Sustained RemissionResults expected Q4 2027
- 2026-02-18ClinicalA Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Upadacitinib in Subjects With Takayasu Arteritis (SELECT-Takayasu)Results expected Q3 2028
- 2026-01-14ClinicalDapagliflozin and Endothelin Receptor Antagonism in Large Vessel Vasculitis (DERAIL-LVV)Results expected Q3 2027
- 2025-12-31ClinicalComparison of the Efficacy and Safety of Tofacitinib and Methotrexate Based on Prednisone Therapy in Patients with Active Phase of Takayasu's Arteritis: a Randomized Controlled TrialPrimary completion
- 2025-12-31ClinicalLow Dose Naltrexone to Improve Physical Health in Patients With VasculitisCompleted
Clinical trials
The current development programme across all trial phases.
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Disease biology
Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.
Reference
Authoritative identity, definition & identifiers.
A chronic inflammatory process that affects the AORTA and its primary branches, such as the brachiocephalic artery (BRACHIOCEPHALIC TRUNK) and CAROTID ARTERIES. It results in progressive arterial stenosis, occlusion, and aneurysm formation. The pulse in the arm is hard to detect. Patients with aortitis syndrome often exhibit retinopathy.
Arteritis, Takayasu, Takayasu's arteritis, Takayasu's disease, aortic arch arteritis, aortic arch syndrome, cervical aortic arch, idiopathic aortitis, pharyngeal arch artery syndromic disease, TA, Takayasu disease, Young female arteritis, pulseless disease
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Related entities are derived from literature co-mention (studied together) — associative, not causal.