PTK2B

Gene

protein tyrosine kinase 2 beta

HGNCHGNC:9612 EnsemblENSG00000120899 NCBI Gene2185

Locus: gene with protein productLocation: 8p21.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCAKB · PYK2 · RAFTK · PTK · CADTK

View full nomenclature history (6)

Alias symbolsCAKB, PYK2, RAFTK, PTK, CADTK

Previous namesFAK2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Autoimmune disorder of central nervous system

Ovarian dysfunction

Squamous cell lung carcinoma

Carcinoma, Non-Small-Cell Lung

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Minor histocompatibility antigensFERM domain containingPTK2 family tyrosine kinasesMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.