FCGR3B

Gene

Fc gamma receptor IIIb

HGNCHGNC:3620 EnsemblENSG00000162747 NCBI Gene2215

Locus: gene with protein productLocation: 1q23.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asFCGR3 · FCG3 · CD16 · HNA-1 · CD16b · FcgammaRIIIb · FcRIIIb

View full nomenclature history (11)

Previous symbolsFCGR3, FCG3

Alias symbolsCD16, HNA-1, CD16b, FcgammaRIIIb, FcRIIIb

Previous namesFc fragment of IgG, low affinity IIIb, receptor for (CD16), Fc fragment of IgG, low affinity IIIb, receptor (CD16b), Fc fragment of IgG receptor IIIb

Alias nameshuman neutrophil antigen 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Takayasu arteritis

Pulmonary Disease, Chronic Obstructive

Arthritis, Rheumatoid

Irritable Bowel Syndrome

Lupus Erythematosus, Systemic

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesImmunoglobulin like domain containingFc receptorsHuman neutrophil antigens

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-02-13.

Open TargetsGene–disease associations from the Open Targets Platform.