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Drug

Benzoyl Peroxide

In clinical development
Emerging researchLate-stage development
Also known as Acanya, Acne, Acne Medication, Acne Treatment+69 more

Acanya, Acne, Acne Medication, Acne Treatment, Acne-10, Acne-5, Acne-Clear, Acnigel, Aktipak, Anti Bac, Ben-Aqua, Benoxyl 10, Benoxyl 5, BenzEFoam, BenzaClin, Benzac, Benzagel Wash, BenzePrO, Benziq, Benziq LS, Benzoyl benzenecarboperoxoate, Brevoxyl, Breze, Cabtreo, Clear By Design, Clear Proof Acne Treatment, Clearplex, Clearskin, Clenziderm Lotion, Del-Aqua, Delos, Desquam, Duac, Effaclar Duo, Enzoclear, Epiduo, Epiduo Forte, Epsolay, Ethexderm, Fostex, Inova, Inova 8-2, Loroxide, Myhelper, NeoBenz Micro, NeoBenz Micro Wash, Neuac, NuOx, OC Eight, OC8, Onexton, Oscion, Pacnex, Peroderm, Peroxin A, Peroxin A 10, Persa-Gel, Peróxido de benzoilo, Phisoderm Clear Confidence Spot Treatment, Relovox, Riax, Seba-Gel, Soluclenz, Triaz, Twyneo, Vanoxide, Vanoxide-HC, Zaclir, Zeroxin, ZoDerm, Benzamycin, Benzoyl Peroxide-Erythromycin, Inova 8/2.

RxNorm1418ChEMBLCHEMBL1200370ATCD10AE01ATCD10AE51UNIIW9WZN9A0GM
1
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Profiling the Skin Microbiome in Response to Altreno in Acne Patients

Clinical trial2024-02-06Results posted · ClinicalTrials.gov

Guidelines of care for the management of acne vulgaris.

Research2024-01-30Journal of the American Academy of Dermatology

Randomized Controlled Trial Comparing the Efficacy of Adapalene 0.1% Gel to 10% Benzoyl Peroxide in Treating Molluscum Contagiosum.

Clinical trial2023-10-09Withdrawn · ClinicalTrials.gov

Can Benzoyl Peroxide Decrease the Burden of Cutibacterium Acnes in Primary Spine and Shoulder Surgery? Prospective Randomized Study

Clinical trial2023-05-01Primary completion · ClinicalTrials.gov

A Multi-Center, Randomized, Double-Blind, Parallel-Group Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel Compared With Adapalene Topical Gel, 0.1%; Benzoyl Peroxide Topical Gel, 2.5% and Topical Gel Vehicle in Subjects With Acne Vulgaris

Clinical trial2021-02-18Results posted · ClinicalTrials.gov

Benzaknen® 5% Gel in Combination With Dermotivin® Soft Liquid Soap and Non-comedogenic Cetaphil® Dermacontrol Moisturizer SPF30 in the Treatment of Mild-to-moderate Acne Vulgaris

Clinical trial2021-02-18Results posted · ClinicalTrials.gov

Measuring Adherence in Subjects With Acne Vulgaris in a Clinic Population Subtitle: Topical Benzoyl Peroxide for Acne

Clinical trial2018-08-28Results posted · ClinicalTrials.gov

A Split-face, Paired-comparison Pilot Study to Evaluate the Safety and Efficacy of Topical Benzoyl Peroxide 2.5% Cream Alone Versus Benzoyl Peroxide 2.5% Cream Plus Moisturizing Lotion for Mild to Moderate Acne Vulgaris

Clinical trial2017-09-26Results posted · ClinicalTrials.gov

A Double Blind Randomised Comparison of Nadifloxacin 1% Cream Alone and Nadifloxacine %1 Cream With Benzoyl Peroxide 5% Solution in the Treatment of Mild to Moderate Facial Acne Vulgaris

Clinical trial2009-06-01Primary completion · ClinicalTrials.gov

A Clinical Study Evaluating the Safety and Efficacy of IDP-110 in Patients With Acne Vulgaris

Clinical trial2008-04-22Completed · ClinicalTrials.gov

A Clinical Trial Evaluating the Safety and Efficacy of IDP-110 in Patients With Acne Vulgaris

Clinical trial2008-04-22Completed · ClinicalTrials.gov

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Benzoyl Peroxide
Aliases & brands
AcanyaAcneAcne MedicationAcne TreatmentAcne-10Acne-5Acne-ClearAcnigelAktipakAnti BacBen-AquaBenoxyl 10Benoxyl 5BenzEFoamBenzaClinBenzacBenzagel WashBenzePrOBenziqBenziq LSBenzoyl benzenecarboperoxoateBrevoxylBrezeCabtreoClear By DesignClear Proof Acne TreatmentClearplexClearskinClenziderm LotionDel-AquaDelosDesquamDuacEffaclar DuoEnzoclearEpiduoEpiduo ForteEpsolayEthexdermFostexInovaInova 8-2LoroxideMyhelperNeoBenz MicroNeoBenz Micro WashNeuacNuOxOC EightOC8OnextonOscionPacnexPerodermPeroxin APeroxin A 10Persa-GelPeróxido de benzoiloPhisoderm Clear Confidence Spot TreatmentRelovoxRiaxSeba-GelSoluclenzTriazTwyneoVanoxideVanoxide-HCZaclirZeroxinZoDermBenzamycinBenzoyl Peroxide-ErythromycinInova 8/2
RxNorm CUI
1418
ChEMBL ID
CHEMBL1200370
ATC codes
D10AE01D10AE51
UNII
W9WZN9A0GM

Clinical trials

10 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
10
registered trials across all phases
LATEST COMPLETION 2022
10
Late-stage (III+)
7
Completed
3
Discontinued
PHASE DISTRIBUTIONn = 10
Phase 35Phase 43Phase N / A2

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Profiling the Skin Microbiome in Response to Altreno in Acne Patients

CompletedPH IVBeth Israel Deaconess Medical Centern=252022

Benzaknen® 5% Gel in Combination With Dermotivin® Soft Liquid Soap and Non-comedogenic Cetaphil® Dermacontrol Moisturizer SPF30 in the Treatment of Mild-to-moderate Acne Vulgaris

CompletedPH IVGalderma R&Dn=502016

Measuring Adherence in Subjects With Acne Vulgaris in a Clinic Population Subtitle: Topical Benzoyl Peroxide for Acne

CompletedPH IVWake Forest Universityn=202008

Randomized Controlled Trial Comparing the Efficacy of Adapalene 0.1% Gel to 10% Benzoyl Peroxide in Treating Molluscum Contagiosum.

WithdrawnPH IIIUniversity of Oklahoma2023

A Double Blind Randomised Comparison of Nadifloxacin 1% Cream Alone and Nadifloxacine %1 Cream With Benzoyl Peroxide 5% Solution in the Treatment of Mild to Moderate Facial Acne Vulgaris

Unknown statusPH IIIMarmara Universityn=902009

Recent completions

Trials that read out recently, adding to the completed evidence base.

Profiling the Skin Microbiome in Response to Altreno in Acne Patients

CompletedPH IVBeth Israel Deaconess Medical Centern=252022

Benzaknen® 5% Gel in Combination With Dermotivin® Soft Liquid Soap and Non-comedogenic Cetaphil® Dermacontrol Moisturizer SPF30 in the Treatment of Mild-to-moderate Acne Vulgaris

CompletedPH IVGalderma R&Dn=502016

Measuring Adherence in Subjects With Acne Vulgaris in a Clinic Population Subtitle: Topical Benzoyl Peroxide for Acne

CompletedPH IVWake Forest Universityn=202008

A Split-face, Paired-comparison Pilot Study to Evaluate the Safety and Efficacy of Topical Benzoyl Peroxide 2.5% Cream Alone Versus Benzoyl Peroxide 2.5% Cream Plus Moisturizing Lotion for Mild to Moderate Acne Vulgaris

CompletedN/ANorthwestern Universityn=112008

A Multi-Center, Randomized, Double-Blind, Parallel-Group Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel Compared With Adapalene Topical Gel, 0.1%; Benzoyl Peroxide Topical Gel, 2.5% and Topical Gel Vehicle in Subjects With Acne Vulgaris

CompletedPH IIIKey trialGalderma R&Dn=1,6702007

A Clinical Trial Evaluating the Safety and Efficacy of IDP-110 in Patients With Acne Vulgaris

CompletedPH IIIKey trialDow Pharmaceutical Sciencesn=1,3992007

Research activity

1 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Most influential

Guidelines of care for the management of acne vulgaris.

Journal of the American Academy of Dermatology · 2024 · 236 cites
Recent papers

Guidelines of care for the management of acne vulgaris.

Journal of the American Academy of Dermatology · 2024 · 236 cites
Major research themes8
Acne Vulgaris1Anti-Bacterial Agents1Benzoyl Peroxide1Dermatologic Agents1Dicarboxylic Acids1Doxycycline1Isotretinoin1Salicylic Acid1
Journals, researchers & institutions
Top journals
  • Journal of the American Academy of Dermatology1
Leading researchers
  • Barbieri JS1
  • Cheng CE1
  • Cook-Bolden F1
  • Desai SR1
  • Druby KM1
  • Freeman EE1
  • Han JM1
  • Keri JE1
Leading institutions
free-text, unnormalised
  • American Academy of Dermatology1
  • Beth Israel Deaconess Medical Center1
  • Brigham and Women's Hospital1
  • Emory University School of Medicine1
  • Massachusetts General Hospital1
  • Mayo Clinic1

Related drugs

8 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Azelaic acid

Studied across the same disease area as Benzoyl Peroxide in the shared literature.

1 shared disease1 shared paper
Clascoterone

Studied across the same disease area as Benzoyl Peroxide in the shared literature.

1 shared disease1 shared paper
Doxycycline

Studied across the same disease area as Benzoyl Peroxide in the shared literature.

1 shared disease1 shared paper
Isotretinoin

Studied across the same disease area as Benzoyl Peroxide in the shared literature.

1 shared disease1 shared paper
Minocycline

Studied across the same disease area as Benzoyl Peroxide in the shared literature.

1 shared disease1 shared paper
Salicylic Acid

Studied across the same disease area as Benzoyl Peroxide in the shared literature.

1 shared disease1 shared paper
Sarecycline

Studied across the same disease area as Benzoyl Peroxide in the shared literature.

1 shared disease1 shared paper
Spironolactone

Studied across the same disease area as Benzoyl Peroxide in the shared literature.

1 shared disease1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials