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Drug

Bromodeoxyuridine

In clinical development
Emerging researchEarly-to-mid developmentCooling momentum

Also known as Broxuridina, Broxuridine.

11
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Cell Kinetic Study of Bromodeoxyuridine (BrdU) in Prostate Cancer

Clinical trial2013-01-25Completed · ClinicalTrials.gov

Reactive astrocytes protect tissue and preserve function after spinal cord injury.

Research2004-03-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Maturation and death of adult-born olfactory bulb granule neurons: role of olfaction.

Research2002-07-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Enriched odor exposure increases the number of newborn neurons in the adult olfactory bulb and improves odor memory.

Research2002-04-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus.

Research2001-03-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus.

Research2000-12-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus.

Research2000-12-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus.

Research2000-04-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Estrogen stimulates a transient increase in the number of new neurons in the dentate gyrus of the adult female rat.

Research1999-07-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Experience-induced neurogenesis in the senescent dentate gyrus.

Research1998-05-01The Journal of neuroscience : the official journal of the Society for Neuroscience

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Bromodeoxyuridine
Aliases & brands
BroxuridinaBroxuridine
RxNorm CUI
1762
ChEMBL ID
CHEMBL222280
UNII
G34N38R2N1

Clinical trials

2 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
2
registered trials across all phases
LATEST COMPLETION 2002
1
Completed
1
Discontinued
PHASE DISTRIBUTIONn = 2
Phase 22

Recent completions

Trials that read out recently, adding to the completed evidence base.

Cell Kinetic Study of Bromodeoxyuridine (BrdU) in Prostate Cancer

CompletedPH IINational Cancer Institute (NCI)n=752002

Research activity

11 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
19972024
Most influential

Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000 · 2,294 cites

Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 1997 · 1,402 cites

Reactive astrocytes protect tissue and preserve function after spinal cord injury.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004 · 1,189 cites

Experience-induced neurogenesis in the senescent dentate gyrus.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 1998 · 750 cites

Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001 · 699 cites

Estrogen stimulates a transient increase in the number of new neurons in the dentate gyrus of the adult female rat.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 1999 · 696 cites
Recent papers

Reactive astrocytes protect tissue and preserve function after spinal cord injury.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004 · 1,189 cites

Maturation and death of adult-born olfactory bulb granule neurons: role of olfaction.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002 · 537 cites

Enriched odor exposure increases the number of newborn neurons in the adult olfactory bulb and improves odor memory.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002 · 466 cites

Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001 · 699 cites

Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000 · 2,294 cites
Major research themes6
Exosomes1HMGB1 Protein1MicroRNAs1Odorants1Status Epilepticus1Stem Cell Transplantation1
Journals, researchers & institutions
Top journals
  • The Journal of neuroscience : the official journal of the Society for Neuroscience10
  • Molecular biology reports1
Leading researchers
  • Gage FH2
  • Aberg MA1
  • Aberg ND1
  • Alvarez-Buylla A1
  • Carro E1
  • Doan NB1
  • Duman RS1
  • Eisch AJ1
Leading institutions
free-text, unnormalised
  • University of California2
  • Institute of Clinical Neuroscience1
  • Laboratory of Molecular Psychiatry1
  • Laboratory of Neuroendocrinology1
  • Perception and Memory Laboratory1
  • Princeton University1

Related diseases

1 conditions

Regulator-approved indications and conditions co-mentioned with this drug across the research literature. Number shows shared papers.

Active research areas

Related drugs

7 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across 4 of the same disease areas as Bromodeoxyuridine in the shared literature.

4 shared diseases1 shared paper

Studied across 4 of the same disease areas as Bromodeoxyuridine in the shared literature.

4 shared diseases1 shared paper

Studied across 3 of the same disease areas as Bromodeoxyuridine in the shared literature.

3 shared diseases1 shared paper

Studied across the same disease area as Bromodeoxyuridine in the shared literature.

1 shared disease1 shared paper

Studied across the same disease area as Bromodeoxyuridine in the shared literature.

1 shared disease1 shared paper

Frequently co-studied with Bromodeoxyuridine in the research literature.

1 shared paper

Frequently co-studied with Bromodeoxyuridine in the research literature.

1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials