Back to discover
Drug

Glycine

In clinical development
Emerging researchLate-stage developmentRising momentum
Also known as Aminoacetic Acid, Aminoessigsäure, Aminoethanoic acid, Aminosyn 10%, Sulfite-Free+44 more

Aminoacetic Acid, Aminoessigsäure, Aminoethanoic acid, Aminosyn 10%, Sulfite-Free, Aminosyn 3.5 % M, Sulfite Free, Aminosyn 8.5 % with Electrolytes, Sulfite-Free, Aminosyn 8.5%, Sulfite-Free, Aminosyn II 10 %, Aminosyn II 15%, Aminosyn II 8.5 % with Electrolytes, Sulfite-Free, Aminosyn II 8.5 %, Sulfite-Free, Aminosyn-HBC 7 %, Sulfite-Free, Aminosyn-PF 10 %, Sulfite-Free, Aminosyn-PF 7%, Clinisol 15, Freamine III 10, Glicina, Gly, Glycine - amino acid, Glycine Oral, Glycocoll, Glykokoll, Hepatamine 8, Hepatasol, Plenamine, PremaSol, ProSol, ProcalAmine 3, Travasol 10, Travasol 10%, Trophamine, Trophamine 10 %, Trophamine 6 %, glycine urologic solution, Glycin, Glyzin, Clinimix 4.25/10, Clinimix 4.25/25, Clinimix 4.25/5, Clinimix 5/15, Clinimix 5/20, Clinimix 5/25, Clinimix E 2.75/5, Clinimix E 4.25/10, Clinimix E 4.25/5, Clinimix E 5/15, Clinimix E 5/20, Clinimix E 5/25.

4
Research papers
1
Active clinical trials
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Static Magnetic Field Stimulation Enhances Shunting Inhibition via a SLC26 Family Cl<sup>-</sup> Channel, Inducing Intrinsic Plasticity.

Research2024-02-28The Journal of neuroscience : the official journal of the Society for Neuroscience

Glycine vs Placebo for the Schizophrenia Prodrome

Clinical trial2020-04-02Results posted · ClinicalTrials.gov

Long-term Impact and Intervention for Diarrhea in Brazil

Clinical trial2011-12-01Primary completion · ClinicalTrials.gov

Adjunctive Glycine for Obsessive Compulsive Disorder

Clinical trial2006-12-01Completed · ClinicalTrials.gov

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Glycine
Aliases & brands
Aminoacetic AcidAminoessigsäureAminoethanoic acidAminosyn 10%, Sulfite-FreeAminosyn 3.5 % M, Sulfite FreeAminosyn 8.5 % with Electrolytes, Sulfite-FreeAminosyn 8.5%, Sulfite-FreeAminosyn II 10 %Aminosyn II 15%Aminosyn II 8.5 % with Electrolytes, Sulfite-FreeAminosyn II 8.5 %, Sulfite-FreeAminosyn-HBC 7 %, Sulfite-FreeAminosyn-PF 10 %, Sulfite-FreeAminosyn-PF 7%Clinisol 15Freamine III 10GlicinaGlyGlycine - amino acidGlycine OralGlycocollGlykokollHepatamine 8HepatasolPlenaminePremaSolProSolProcalAmine 3Travasol 10Travasol 10%TrophamineTrophamine 10 %Trophamine 6 %glycine urologic solutionGlycinGlyzinClinimix 4.25/10Clinimix 4.25/25Clinimix 4.25/5Clinimix 5/15Clinimix 5/20Clinimix 5/25Clinimix E 2.75/5Clinimix E 4.25/10Clinimix E 4.25/5Clinimix E 5/15Clinimix E 5/20Clinimix E 5/25
RxNorm CUI
4919
ChEMBL ID
CHEMBL773
ATC codes
B05CX03
UNII
TE7660XO1C

Clinical trials

13 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
13
registered trials across all phases
LATEST COMPLETION 2017
1
Active studies
1
Recruiting
8
Late-stage (III+)
7
Completed
5
Discontinued
PHASE DISTRIBUTIONn = 13
Phase 25Phase 2 / 32Phase 34Phase 41Phase N / A1

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Recent completions

Trials that read out recently, adding to the completed evidence base.

Glycine vs Placebo for the Schizophrenia Prodrome

CompletedPH II/IIIYale Universityn=82009

Adjunctive Glycine for Obsessive Compulsive Disorder

CompletedN/ANathan Kline Institute for Psychiatric Researchn=242006

Glycine Treatment of Prodromal Symptoms

CompletedPH IIYale Universityn=102004

Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST)

CompletedPH II/IIIUniversity of Maryland, Baltimoren=2402004

Research activity

4 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20012024
Most influential
Recent papers
Major research themes6
Amino Acid Substitution1Bile Duct Neoplasms1Chlorides1Cholangiocarcinoma1Hydrazines1Magnetic Fields1
Journals, researchers & institutions
Top journals
  • The Journal of neuroscience : the official journal of the Society for Neuroscience2
  • Cell1
  • JAMA oncology1
Leading researchers
  • Abou-Alfa GK1
  • Adeva J1
  • Aguado-Fraile E1
  • Akita T1
  • Albuquerque EX1
  • Alkondon M1
  • Borad MJ1
  • Bridgewater JA1
Leading institutions
free-text, unnormalised
  • Dana-Farber Cancer Institute1
  • Department of Pharmacology and Experimental Therapeutics and Maryland Psychiatric Research Center1
  • Hamamatsu University School of Medicine1
  • Helen Diller Family Comprehensive Cancer Center1
  • Hokkaido University1
  • Hospital Universitario 12 de Octubre1

Related drugs

5 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across 2 of the same disease areas as Glycine in the shared literature.

2 shared diseases1 shared paper

Studied across the same disease area as Glycine in the shared literature.

1 shared disease1 shared paper

Frequently co-studied with Glycine in the research literature.

1 shared paper

Frequently co-studied with Glycine in the research literature.

1 shared paper

Frequently co-studied with Glycine in the research literature.

1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials