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Drug

Sucrose

In clinical development
Emerging researchLate-stage developmentRising momentum
Also known as 1-alpha-D-Glucopyranosyl-2-beta-D-fructofuranoside, Beet sugar, Cane sugar, Sacarosa+5 more

1-alpha-D-Glucopyranosyl-2-beta-D-fructofuranoside, Beet sugar, Cane sugar, Sacarosa, Saccharose, Sacharose, Sucraloxum, TootSweet, White sugar.

RxNorm10159ChEMBLCHEMBL253582UNIIC151H8M554
3
Research papers
1
Active clinical trials
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Sucrose-derived carbon spheres for rapid solid-phase extraction and trace cadmium removal from aqueous media

Industry2026-07-21Nature — Environmental Sciences

Effect of the Consumption of Beverages Added With Stevia Rebaudiana on Oral pH and Dental Biofilm in Adolescents

Clinical trial2025-12-01Primary completion · ClinicalTrials.gov

High-fat and high-sucrose diet impairs female reproduction by altering ovarian transcriptomic and metabolic signatures.

Research2024-02-12Journal of translational medicine

Einfluss Des süßmodulierenden Polyphenols Hesperetin in Kombination Mit Saccharose Auf Die Blutglukose-Regulierung Und Energieaufnahme in Abhängigkeit Der Süßwahrnehmung

Clinical trial2023-11-15Completed · ClinicalTrials.gov

A Randomized, Controlled, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy of Intravenous Iron Sucrose in Patients With Non-anemic Iron Deficiency and Postural Orthostatic Tachycardia Syndrome (POTS)

Clinical trial2023-05-01Withdrawn · ClinicalTrials.gov

Einfluss Der Süßintensität Einer Saccharose-Lösung Auf Die Blutglukoseregulation Und Energieaufnahme in Gesunden Männern

Clinical trial2022-12-30Completed · ClinicalTrials.gov

Effect of Probiotic on Rhinovirus Induced Colds

Clinical trial2020-03-25Results posted · ClinicalTrials.gov

Phase I/II Study AC6 Gene Transfer for Congestive Heart Failure

Clinical trial2017-11-16Completed · ClinicalTrials.gov

Analgesia for Neonatal Circumcision: A Randomized Controlled Clinical Trial of EMLA Versus Combination of EMLA, Sucrose and Dorsal Penile Nerve Block or Ring Block

Clinical trial2017-01-01Completed · ClinicalTrials.gov

Is There a Difference in Pain Score, Stress Response and Motor Repertoire in Infants Given Skin-to-skin Contact With the Mother/Father or Standard Care During Screening for Retinopathy?

Clinical trial2016-06-01Completed · ClinicalTrials.gov

Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease.

Research2011-12-01PloS one

MAPMAN: a user-driven tool to display genomics data sets onto diagrams of metabolic pathways and other biological processes.

Research2004-03-01The Plant journal : for cell and molecular biology

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Sucrose
Aliases & brands
1-alpha-D-Glucopyranosyl-2-beta-D-fructofuranosideBeet sugarCane sugarSacarosaSaccharoseSacharoseSucraloxumTootSweetWhite sugar
RxNorm CUI
10159
ChEMBL ID
CHEMBL253582
UNII
C151H8M554

Clinical trials

19 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
19
registered trials across all phases
LATEST COMPLETION 2023
1
Active studies
1
Recruiting
12
Late-stage (III+)
13
Completed
5
Discontinued
PHASE DISTRIBUTIONn = 19
Early Phase 12Phase 1 / 22Phase 23Phase 2 / 31Phase 33Phase 41Phase N / A7

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Pneumococcal Vaccination for Splenectomised Thalassemia Major Patients in Indonesia

CompletedPH IVFakultas Kedokteran Universitas Indonesian=562014

Analgesia for Neonatal Circumcision: A Randomized Controlled Clinical Trial of EMLA Versus Combination of EMLA, Sucrose and Dorsal Penile Nerve Block or Ring Block

CompletedPH IIIAmerican University of Beirut Medical Centern=702017

A Randomized Controlled Trial of Rotavirus Vaccine vs. Sugar Water for Vaccine Injection Pain Management in Infants

Unknown statusPH IIIAnna Taddion=1202016

Effectiveness of Parent-Led Interventions in Reducing Infant Hypersensitivity to Pain: A Longitudinal Randomized Controlled Trial

Unknown statusPH IIIThe Hospital for Sick Childrenn=3522016

A Study to Assess the Role of Oral Sucrose in Reducing the Pain to Orogastric Tube Insertion in Preterm Neonates

CompletedPH II/IIILady Hardinge Medical Collegen=1202009

Recent completions

Trials that read out recently, adding to the completed evidence base.

Einfluss Des süßmodulierenden Polyphenols Hesperetin in Kombination Mit Saccharose Auf Die Blutglukose-Regulierung Und Energieaufnahme in Abhängigkeit Der Süßwahrnehmung

CompletedPH IUniversity of Viennan=332023

Einfluss Der Süßintensität Einer Saccharose-Lösung Auf Die Blutglukoseregulation Und Energieaufnahme in Gesunden Männern

CompletedPH IUniversity of Viennan=302022

Effect of Probiotic on Rhinovirus Induced Colds

CompletedN/AUniversity of Virginian=3802018

Phase I/II Study AC6 Gene Transfer for Congestive Heart Failure

CompletedPH I/IIHammond, H. Kirk, M.D.n=562017

Analgesia for Neonatal Circumcision: A Randomized Controlled Clinical Trial of EMLA Versus Combination of EMLA, Sucrose and Dorsal Penile Nerve Block or Ring Block

CompletedPH IIIAmerican University of Beirut Medical Centern=702017

Is There a Difference in Pain Score, Stress Response and Motor Repertoire in Infants Given Skin-to-skin Contact With the Mother/Father or Standard Care During Screening for Retinopathy?

CompletedN/ASt. Olavs Hospitaln=342016

Research activity

3 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20042024
Major research themes5
Data Display1Diabetes Mellitus, Type 21Oxidative Stress1Polycystic Ovary Syndrome1Software1
Journals, researchers & institutions
Top journals
  • Journal of translational medicine1
  • PloS one1
  • The Plant journal : for cell and molecular biology1
Leading researchers
  • Bläsing O1
  • Chen ZJ1
  • Dodiya HB1
  • Dou Y1
  • Estes JD1
  • Forsyth CB1
  • Gibon Y1
  • Han S1
Leading institutions
free-text, unnormalised
  • Chinese Academy of Medical Sciences (No. 2021RU001)1
  • Institute of Women1
  • Key Laboratory of Reproductive Endocrinology (Shandong University)1
  • Max Planck Institute for Molecular Plant Physiology1
  • National Research Center for Assisted Reproductive Technology and Reproductive Genetics1
  • Ren Ji Hospital1

Related drugs

5 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Trichlorosucrose

Studied across 2 of the same disease areas as Sucrose in the shared literature.

2 shared diseases1 shared paper
Ethylene

Frequently co-studied with Sucrose in the research literature.

1 shared paper
Nitrates

Frequently co-studied with Sucrose in the research literature.

1 shared paper
Starch

Frequently co-studied with Sucrose in the research literature.

1 shared paper
Trehalose

Frequently co-studied with Sucrose in the research literature.

1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials