Drug

Thyrotropin

Research stage

ClassThyroid stimulating hormone receptor agonistEmerging researchSteady momentum

Also known as TSH - thyroid stimulating hormone, Thyroid stimulating hormone, THYROTROPHIN.

RxNorm10579 ChEMBLCHEMBL1201532 ATCV04CJ01UNII02KSI6Z9AK

Research papers

Thyrotropin receptor

Primary target

Latest activity

beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Central and Peripheral Sensitivity to Thyroid Hormones Correlate to Metabolically Obesity Phenotypes in Chinese Euthyroid Adults: A Cross-Sectional Study.

Research2024-11-01Diabetes/metabolism research and reviews

Prevalence of subclinical hypothyroidism and longitudinal thyroid-stimulating hormone changes in youth with metabolic dysfunction-associated steatotic liver disease: An observational study.

Research2024-09-18Hepatology (Baltimore, Md.)

Thyroid Hormone Homeostasis in Levothyroxine-treated Patients: Findings From ELSA-Brasil.

Research2024-09-01The Journal of clinical endocrinology and metabolism

Associations between sensitivity to thyroid hormones and insulin resistance in euthyroid adults with obesity.

Research2024-08-08Frontiers in endocrinology

Implications of GLP-1 Receptor Agonist on Thyroid Function: A Literature Review of Its Effects on Thyroid Volume, Risk of Cancer, Functionality and TSH Levels.

Research2024-06-13Biomolecules

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.

Research2024-01-30Nature communications

Subclinical Hypothyroidism in Patients with Obesity and Metabolic Syndrome: A Narrative Review.

Research2023-12-27Nutrients

Predictors of controlled attenuation parameter in metabolic dysfunction.

Research2023-12-23United European gastroenterology journal

Effects of vitamin D supplementation on metabolic parameters, serum irisin and obesity values in women with subclinical hypothyroidism: a double-blind randomized controlled trial.

Research2023-12-21Frontiers in endocrinology

Environmental Endocrinology: Parabens Hazardous Effects on Hypothalamic-Pituitary-Thyroid Axis.

Research2023-10-17International journal of molecular sciences

Thyroid hormone sensitivity and diabetes onset: a longitudinal cross-lagged cohort.

Research2023-10-16Frontiers in endocrinology

Thyroid Stimulating Hormone and Thyroid Hormones (Triiodothyronine and Thyroxine): An American Thyroid Association-Commissioned Review of Current Clinical and Laboratory Status.

Research2023-09-01Thyroid : official journal of the American Thyroid Association

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name

Thyrotropin

Aliases & brands

TSH - thyroid stimulating hormoneThyroid stimulating hormoneTHYROTROPHIN

RxNorm CUI

10579

ChEMBL ID

CHEMBL1201532

ATC codes

V04CJ01

UNII

02KSI6Z9AK

Primary mechanism

Thyroid stimulating hormone receptor agonist

Pharmacology & targets

1 target

Known molecular targets and mechanisms supported by curated pharmacology databases.

Thyrotropin receptor

TSHR · P16473

AGONISTThyroid stimulating hormone receptor agonist

Research activity

16 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time

20192025

Most influential

Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis.

JAMA · 2019 · 233 cites

Thyrotoxicosis in patients with COVID-19: the THYRCOV study.

European journal of endocrinology · 2020 · 232 cites

Thyroid-Gut-Axis: How Does the Microbiota Influence Thyroid Function?

Nutrients · 2020 · 214 cites

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.

Nature communications · 2024 · 62 cites

Thyroid Stimulating Hormone and Thyroid Hormones (Triiodothyronine and Thyroxine): An American Thyroid Association-Commissioned Review of Current Clinical and Laboratory Status.

Thyroid : official journal of the American Thyroid Association · 2023 · 43 cites

Subclinical Hypothyroidism in Patients with Obesity and Metabolic Syndrome: A Narrative Review.

Nutrients · 2023 · 43 cites

Related diseases

4 conditions

Regulator-approved indications and conditions co-mentioned with this drug across the research literature. Number shows shared papers.

Active research areas

Hypothyroidism6 Obesity4 Thyroid Diseases2 Thyroid Neoplasms2

Related drugs

5 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Thyroxine

Studied across 9 of the same disease areas as Thyrotropin in the shared literature.

9 shared diseases7 shared papers

Vitamin D

Studied across 17 of the same disease areas as Thyrotropin in the shared literature.

17 shared diseases2 shared papers

Triiodothyronine

Studied across 8 of the same disease areas as Thyrotropin in the shared literature.

8 shared diseases5 shared papers

Iodine

Studied across 6 of the same disease areas as Thyrotropin in the shared literature.

6 shared diseases1 shared paper

Parabens

Frequently co-studied with Thyrotropin in the research literature.

1 shared paper

References & data sources

RxNorm (U.S. National Library of Medicine) — drug identity
ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
Europe PMC — research literature