ABT1

Gene

activator of basal transcription 1

HGNCHGNC:17369 EnsemblENSG00000146109 NCBI Gene29777

Locus: gene with protein productLocation: 6p22.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asEsf2

View full nomenclature history (1)

Alias symbolsEsf2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Sudden infant death syndrome

Lupus Erythematosus, Systemic

Scleroderma, Systemic

Nervous System Diseases

Cerebellar Ataxia

Connective Tissue Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

SSU processome

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.