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ACAN

Gene

aggrecan

HGNCHGNC:319EnsemblENSG00000157766NCBI Gene176
Locus: gene with protein productLocation: 15q26.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMSK16 · CSPG1 · AGC1 · CSPGCP
View full nomenclature history (7)
Previous symbolsMSK16, CSPG1, AGC1
Alias symbolsCSPGCP
Previous nameschondroitin sulfate proteoglycan 1, aggrecan 1
Alias namesaggrecan proteoglycan

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn
Osteoarthritis, Knee
Osteoarthritis, Hip
Osteoarthritis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Hyalectan proteoglycansV-set domain containingSushi domain containingC-type lectin domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.