ADAM10

Gene

ADAM metallopeptidase domain 10

HGNCHGNC:188 EnsemblENSG00000137845 NCBI Gene102

Locus: gene with protein productLocation: 15q21.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known askuz · MADM · HsT18717 · CD156C

View full nomenclature history (5)

Alias symbolskuz, MADM, HsT18717, CD156C

Previous namesa disintegrin and metalloproteinase domain 10

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Alzheimer's Disease

Schizophrenia

Aortic Valve Stenosis

late-onset Alzheimers disease

Aortic Aneurysm

Aneurysm

Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

ADAM metallopeptidase domain containingCD molecules

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.