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ASIC2

Gene

acid sensing ion channel subunit 2

HGNCHGNC:99EnsemblENSG00000108684NCBI Gene40
Locus: gene with protein productLocation: 17q11.2-q12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asACCN · ACCN1 · ASIC2a · BNC1 · BNaC1 · hBNaC1 · MDEG
View full nomenclature history (11)
Previous symbolsACCN, ACCN1
Alias symbolsASIC2a, BNC1, BNaC1, hBNaC1, MDEG
Previous namesamiloride-sensitive cation channel 1, neuronal, acid-sensing (proton-gated) ion channel 2
Alias namesdegenerin, brain Na+ channel-1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Alcohol drinking
Smoking initiation
Major depressive disorder
Cardiomyopathy, Hypertrophic
Gastrointestinal disease
Stroke

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Acid sensing ion channel subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-06-26.
Open TargetsGene–disease associations from the Open Targets Platform.