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ATL1

Gene

atlastin GTPase 1

HGNCHGNC:11231EnsemblENSG00000198513NCBI Gene51062
Locus: gene with protein productLocation: 14q22.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSPG3 · SPG3A · FSP1 · AD-FSP
View full nomenclature history (6)
Previous symbolsSPG3, SPG3A
Alias symbolsFSP1, AD-FSP
Previous namesspastic paraplegia 3A (autosomal dominant)
Alias namesatlastin

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Spastic Paraplegia, Hereditary
Genetic Diseases, Inborn
Hereditary sensory and autonomic neuropathy
Dupuytren Contracture

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Atlastins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.