BECN1

Gene

beclin 1

HGNCHGNC:1034 EnsemblENSG00000126581 NCBI Gene8678

Locus: gene with protein productLocation: 17q21.31

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Beclin-1Q14457

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asATG6 · VPS30

View full nomenclature history (5)

Alias symbolsATG6, VPS30

Previous namesbeclin 1 (coiled-coil, moesin-like BCL2 interacting protein), beclin 1, autophagy related

Alias namesATG6 autophagy related 6 homolog (S. cerevisiae)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

COVID-19

Dengue

Severe Acute Respiratory Syndrome

Lysosomal Storage Diseases

Neoplasms

Carcinoma, Hepatocellular

Breast Neoplasms

Colorectal Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Autophagy relatedPIK3C3 complex subunitsMicroRNA protein coding host genesBeclin family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.