BMAL1

Gene

basic helix-loop-helix ARNT like 1

HGNCHGNC:701 EnsemblENSG00000133794 NCBI Gene406

Locus: gene with protein productLocation: 11p15.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asARNTL · PASD3 · bHLHe5 · ARNTL1 · JAP3 · MOP3

View full nomenclature history (11)

Previous symbolsARNTL

Alias symbolsPASD3, bHLHe5, ARNTL1, JAP3, MOP3

Previous namesaryl hydrocarbon receptor nuclear translocator like

Alias namesbrain and muscle ARNT-like 1, basic helix-loop-helix family member e5, PAS domain containing 3, member of PAS superfamily 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hypertension

Osteoarthritis

Coronary Artery Disease

Osteoarthritis, Knee

Diabetes Mellitus, Type 2

Spondylosis

Essential Hypertension

Musculoskeletal Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Basic helix-loop-helix proteinsPAS domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.

Open TargetsGene–disease associations from the Open Targets Platform.