BPIFA1

Gene

BPI fold containing family A member 1

HGNCHGNC:15749 EnsemblENSG00000198183 NCBI Gene51297

Locus: gene with protein productLocation: 20q11.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPLUNC · LUNX · bA49G10.5 · SPLUNC1

View full nomenclature history (6)

Previous symbolsPLUNC

Alias symbolsLUNX, bA49G10.5, SPLUNC1

Previous namespalate, lung and nasal epithelium carcinoma associated, palate, lung and nasal epithelium associated

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Alzheimer's Disease

Lysosomal Storage Diseases

Multiple Sclerosis

Parkinson's Disease

Cystic Fibrosis

Nasopharyngeal Carcinoma

Carcinoma, Non-Small-Cell Lung

Neoplasms

Pulmonary Disease, Chronic Obstructive

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

BPI fold containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.