CA2

Gene

carbonic anhydrase 2

HGNCHGNC:1373 EnsemblENSG00000104267 NCBI Gene760

Locus: gene with protein productLocation: 8q21.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Carbonic anhydrase 2P00918

Protein · therapeutic target

Clinically validated target · 11 approved medicines against this target

Member of “Carbonic Anhydrases” · 1 related family paper (context, not papers about this gene)

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCar2 · CA-II · CAII

View full nomenclature history (4)

Alias symbolsCar2, CA-II, CAII

Previous namescarbonic anhydrase II

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Osteopetrosis with renal tubular acidosis

Autosomal recessive osteopetrosis 3

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Carbonic anhydrases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.