CBLL1

Gene

Cbl proto-oncogene like 1

HGNCHGNC:21225 EnsemblENSG00000105879 NCBI Gene79872

Locus: gene with protein productLocation: 7q22.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asHAKAI · FLJ23109 · RNF188

View full nomenclature history (7)

Alias symbolsHAKAI, FLJ23109, RNF188

Previous namesCas-Br-M (murine) ecotropic retroviral transforming sequence-like 1, Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase, Cbl proto-oncogene like 1, E3 ubiquitin protein ligase

Alias namesCasitas B-lineage lymphoma-like

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Listeriosis

Lysosomal Storage Diseases

Systemic Inflammatory Response Syndrome

Neoplasms

Carcinoma, Non-Small-Cell Lung

Carcinoma, Hepatocellular

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ring finger proteinsm6A methyltransferase complexWTAP complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.