CD44

Gene

CD44 molecule (IN blood group)

HGNCHGNC:1681 EnsemblENSG00000026508 NCBI Gene960

Locus: gene with protein productLocation: 11p13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMIC4 · MDU2 · MDU3 · IN · MC56 · Pgp1 · PGP-1 · CD44R · HCELL · CSPG8 · Hermes-1 · CDw44 · HUTCH-1 · HUTCH-I · ECM-III · H-CAM

View full nomenclature history (23)

Previous symbolsMIC4, MDU2, MDU3

Alias symbolsIN, MC56, Pgp1, PGP-1, CD44R, HCELL, CSPG8, Hermes-1, CDw44, HUTCH-1, HUTCH-I, ECM-III, H-CAM

Previous namesCD44 antigen (homing function and Indian blood group system)

Alias nameshematopoietic cell E- and L-selectin ligand, chondroitin sulfate proteoglycan 8, phagocyte glycoprotein 1, In(Lu) related-p80, extracellular matrix receptor-III, homing cell adhesion molecule

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Nephrolithiasis

Lupus Erythematosus, Systemic

Hypothyroidism

Autoimmune Diseases

Liver Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Blood group antigensCD moleculesProteoglycans

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-01-22.

Open TargetsGene–disease associations from the Open Targets Platform.