CD58

Gene

CD58 molecule

HGNCHGNC:1688 EnsemblENSG00000116815 NCBI Gene965

Locus: gene with protein productLocation: 1p13.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLFA3

View full nomenclature history (2)

Previous symbolsLFA3

Previous namesCD58 antigen, (lymphocyte function-associated antigen 3)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Multiple Sclerosis

Primary biliary cholangitis

Lymphoma, Large B-Cell, Diffuse

Lymphoma, Non-Hodgkin's

Lupus Erythematosus, Systemic

Joint Diseases

Neoplasms

Carcinoma, Hepatocellular

Central Nervous System Neoplasms

Glioma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesIg-like cell adhesion molecule familyMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.