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CD81

Gene

CD81 molecule

HGNCHGNC:1701EnsemblENSG00000110651NCBI Gene975
Locus: gene with protein productLocation: 11p15.5

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTAPA1 · TAPA-1 · TSPAN28 · S5.7
View full nomenclature history (6)
Previous symbolsTAPA1
Alias symbolsTAPA-1, TSPAN28, S5.7
Previous namesCD81 antigen (target of antiproliferative antibody 1)
Alias namesTetraspanin-28

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Common variable immunodeficiency
Diabetes Mellitus, Type 2
Stroke
Alcohol drinking
Glioblastoma
Infections
Carcinoma, Hepatocellular

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesTetraspanin familyGamete adhesion and fusion factors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.