CDK5RAP2

Gene

CDK5 regulatory subunit associated protein 2

HGNCHGNC:18672 EnsemblENSG00000136861 NCBI Gene55755

Locus: gene with protein productLocation: 9q33.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMCPH3 · C48 · FLJ10867 · CEP215

View full nomenclature history (6)

Previous symbolsMCPH3

Alias symbolsC48, FLJ10867, CEP215

Previous namesmicrocephaly, primary autosomal recessive 3

Alias namescentrosomin

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Autosomal recessive primary microcephaly

Genetic Diseases, Inborn

Bipolar Disorder

Neurodegenerative Diseases

Microcephaly

Arthritis, Rheumatoid

Neutropenia

Placental abruption

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Centriolar satellite proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.