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CHRNB4

Gene

cholinergic receptor nicotinic beta 4 subunit

HGNCHGNC:1964EnsemblENSG00000117971NCBI Gene1143
Locus: gene with protein productLocation: 15q25.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

View full nomenclature history (4)
Previous namescholinergic receptor, nicotinic, beta polypeptide 4, cholinergic receptor, nicotinic, beta 4 (neuronal), cholinergic receptor, nicotinic beta 4
Alias namesacetylcholine receptor, nicotinic, beta 4 (neuronal)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hypertension
Pulmonary Disease, Chronic Obstructive
Aneurysm
Autoimmune disorder of central nervous system
Dupuytren Contracture
Frontotemporal Dementia
Myocardial Ischemia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cholinergic receptors nicotinic subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.