COPS3

Gene

COP9 signalosome subunit 3

HGNCHGNC:2239 EnsemblENSG00000141030 NCBI Gene8533

Locus: gene with protein productLocation: 17p11.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSGN3 · CSN3

View full nomenclature history (4)

Alias symbolsSGN3, CSN3

Previous namesCOP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 3, COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Diabetes Mellitus, Type 2

COVID-19

Carcinoma, Squamous Cell

Adenocarcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

COP9 signalosome

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-26.

Open TargetsGene–disease associations from the Open Targets Platform.