CXCL10

Gene

C-X-C motif chemokine ligand 10

HGNCHGNC:10637 EnsemblENSG00000169245 NCBI Gene3627

Locus: gene with protein productLocation: 4q21.1

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

C-X-C motif chemokine 10P02778

Protein · therapeutic target

Clinical-stage target · 2 candidates in clinical development

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSCYB10 · INP10 · IFI10 · crg-2 · mob-1 · C7 · gIP-10 · IP-10

View full nomenclature history (10)

Previous symbolsSCYB10, INP10

Alias symbolsIFI10, crg-2, mob-1, C7, gIP-10, IP-10

Previous namessmall inducible cytokine subfamily B (Cys-X-Cys), member 10, chemokine (C-X-C motif) ligand 10

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Arthritis, Rheumatoid

Lupus Erythematosus, Systemic

Carcinoma, Hepatocellular

Lung carcinoma

Scleroderma, Systemic

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Chemokine ligands

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.