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CYP2C19

Gene

cytochrome P450 family 2 subfamily C member 19

HGNCHGNC:2621EnsemblENSG00000165841NCBI Gene1557
Locus: gene with protein productLocation: 10q23.33

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Cytochrome P450 2C19P33261

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCYP2C · P450IIC19 · CPCJ
View full nomenclature history (5)
Previous symbolsCYP2C
Alias symbolsP450IIC19, CPCJ
Previous namescytochrome P450, family 2, subfamily C, polypeptide 19, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Acute Coronary Syndrome
Rheumatic Diseases
Ovarian neoplasm
Coronary Artery Disease
Stroke

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cytochrome P450 family 2

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-06-10.
Open TargetsGene–disease associations from the Open Targets Platform.