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DNAJB1

Gene

DnaJ heat shock protein family (Hsp40) member B1

HGNCHGNC:5270EnsemblENSG00000132002NCBI Gene3337
Locus: gene with protein productLocation: 19p13.12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asHSPF1 · Hsp40 · Sis1 · RSPH16B
View full nomenclature history (6)
Previous symbolsHSPF1
Alias symbolsHsp40, Sis1, RSPH16B
Previous namesDnaJ (Hsp40) homolog, subfamily B, member 1
Alias namesradial spoke 16 homolog B (Chlamydomonas)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Adenoma, Liver Cell
Carcinoma, Hepatocellular
Alcohol drinking
Urolithiasis
Smoking initiation
Risk-taking behaviour

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

DNAJ (HSP40) heat shock proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.