ECT2L

Gene

epithelial cell transforming 2 like

HGNCHGNC:21118 EnsemblENSG00000203734 NCBI Gene345930

Locus: gene with protein productLocation: 6q24.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC6orf91 · ARHGEF32 · FBXO49 · LFDH

View full nomenclature history (8)

Previous symbolsC6orf91

Alias symbolsARHGEF32, FBXO49, LFDH

Previous namesepithelial cell transforming sequence 2 oncogene-like, chromosome 6 open reading frame 91

Alias nameslung specific F-box and DH domain containing protein, F-box protein 49

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Wounds and Injuries

Empyema, Pleural

Male reproductive organ cancer

Osteosarcoma

Urinary bladder carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

F-boxes otherDbl family Rho GEFs

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.